Oklahoma Childcare Licensing

Oklahoma Childcare Immunization Requirements (2026)

Children enrolled in a licensed Oklahoma childcare center must show proof of age-appropriate immunization. Oklahoma requires documentation for 9 vaccine series, with limited medical and legally permitted exemptions.

Licensing Agency

Oklahoma Department of Human Services (OKDHS), Child Care Services (CCS) / Licensing →

Last updated: April 2026

Researched by the TotReady Research Team

Oklahoma Immunization Requirements: The Specifics

Oklahoma childcare licensing requires age-appropriate Hepatitis B (Hep B) immunization for enrolled children (subject to documented medical or legally permitted exemptions).

Oklahoma childcare licensing requires age-appropriate Diphtheria, Tetanus & Pertussis (DTaP) immunization for enrolled children (subject to documented medical or legally permitted exemptions).

Oklahoma childcare licensing requires age-appropriate Haemophilus influenzae type b (Hib) immunization for enrolled children (subject to documented medical or legally permitted exemptions).

Oklahoma childcare licensing requires age-appropriate Polio (IPV) immunization for enrolled children (subject to documented medical or legally permitted exemptions).

Oklahoma childcare licensing requires age-appropriate Measles, Mumps & Rubella (MMR) immunization for enrolled children (subject to documented medical or legally permitted exemptions).

Oklahoma childcare licensing requires age-appropriate Varicella/Chickenpox (not required if a parent or treating physician statement confirms the child had chickenpox) immunization for enrolled children (subject to documented medical or legally permitted exemptions).

Oklahoma childcare licensing requires age-appropriate Pneumococcal conjugate (PCV) immunization for enrolled children (subject to documented medical or legally permitted exemptions).

Oklahoma childcare licensing requires age-appropriate Hepatitis A (Hep A) immunization for enrolled children (subject to documented medical or legally permitted exemptions).

Oklahoma childcare licensing requires age-appropriate Required per OAC 340 Appendix II (Immunizations) and 10 O.S. § 411; child care immunization mandate is in 10 O.S. § 411 (not § 281.4). Records or a valid OSDH Form ODH 216A exemption (medical/religious/personal) must be maintained; a one-time 30-calendar-day grace period is allowed. Schedule administered per Oklahoma State Department of Health (OSDH). immunization for enrolled children (subject to documented medical or legally permitted exemptions).

Oklahoma Immunization Requirements Checklist

  • Hepatitis B (Hep B)
  • Diphtheria, Tetanus & Pertussis (DTaP)
  • Haemophilus influenzae type b (Hib)
  • Polio (IPV)
  • Measles, Mumps & Rubella (MMR)
  • Varicella/Chickenpox (not required if a parent or treating physician statement confirms the child had chickenpox)
  • Pneumococcal conjugate (PCV)
  • Hepatitis A (Hep A)
  • Required per OAC 340 Appendix II (Immunizations) and 10 O.S. § 411; child care immunization mandate is in 10 O.S. § 411 (not § 281.4). Records or a valid OSDH Form ODH 216A exemption (medical/religious/personal) must be maintained; a one-time 30-calendar-day grace period is allowed. Schedule administered per Oklahoma State Department of Health (OSDH).

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Oklahoma Immunization Requirements: Frequently Asked Questions

Which vaccines does Oklahoma require for childcare enrollment?

Oklahoma requires age-appropriate immunization records for: Hepatitis B (Hep B), Diphtheria, Tetanus & Pertussis (DTaP), Haemophilus influenzae type b (Hib), Polio (IPV), Measles, Mumps & Rubella (MMR), Varicella/Chickenpox (not required if a parent or treating physician statement confirms the child had chickenpox), Pneumococcal conjugate (PCV), Hepatitis A (Hep A), Required per OAC 340 Appendix II (Immunizations) and 10 O.S. § 411; child care immunization mandate is in 10 O.S. § 411 (not § 281.4). Records or a valid OSDH Form ODH 216A exemption (medical/religious/personal) must be maintained; a one-time 30-calendar-day grace period is allowed. Schedule administered per Oklahoma State Department of Health (OSDH)..

Are immunization exemptions allowed in Oklahoma?

Oklahoma permits documented medical exemptions and, where state law allows, certain non-medical exemptions. Confirm the current exemption rules with the Oklahoma Department of Human Services (OKDHS), Child Care Services (CCS) / Licensing.

When must immunization records be on file in Oklahoma?

Oklahoma requires up-to-date immunization documentation at enrollment, with records kept current in each child's file thereafter.

Oklahoma childcare licensing rules are amended regularly. This page is compiled from published Oklahoma administrative codes and statutes for informational purposes only — always verify current requirements with the Oklahoma Department of Human Services (OKDHS), Child Care Services (CCS) / Licensing before relying on them. TotReady provides information and document templates, not legal or regulatory advice.